โรคพาร์กินสัน หรือโรคสั่นสันนิบาต

โรคพาร์กินสัน หรือโรคสั่นสันนิบาต

โรคพาร์กินสัน เป็นโรคทางระบบประสาทที่พบได้บ่อยในผู้สูงอายุ เริ่มเป็นที่รู้จักในวงการแพทย์ตั้งแต่ราวสองร้อยปีก่อน โดยในอดีตมักเข้าใจว่าโรคนี้มีความผิดปกติที่ไขสันหลัง แต่ปัจจุบันนี้ทราบชัดแล้ว่า พยาธิสภาพของโรคพาร์กินสัน เกิดขึ้นที่เนื้อสมองส่วนลึก ในระยะแรก ๆ ของโรคแพทย์จะยังไม่สามารถวินิจฉัยได้ แต่เมื่อติดตามผู้ป่วยไปสักระยะหนึ่งอาการต่าง ๆ ก็จะปรากฎชัดเจนขึ้น

กลไกการเกิดโรคพาร์กินสันนั้น เกี่ยวข้องกับสารเคมีในสมองก็คือ โดพามีน และอะซิทิลโคลีน โดยปกติจะอยู่ในสภาวะสมดุล แต่เมื่อเซลล์สมองที่สร้างโดพามีนตายไปก็จะเสียสมดุล จนทำให้ร่างกายเสียสมดุล เคลื่อนไหวผิดปกติ จนกลายเป็นโรคพาร์กินสัน ซึ่งอาการทางระบบประสาทที่โดดเด่นของพาร์กินสันมีอยู่สามประกอรได้แก่ อาการเกร็ง สั่น และเคลื่อนไหวได้ช้า

แนวทางในการรักษาโรคพาร์กินสัน มีหลักก็คือต้องเพิ่มระดับของสารโดพามีนในสมอง ด้วยการให้ยาหรือการกระตุ้นสมองให้สร้างโดปามีนเพิ่มขึ้น เพื่อบรรเทาอาการต่าง ๆ ของโรคและป้องกันโรคแทรกซ้อน แต่สำหรับผู้ที่ใช้ยาไม่ได้ผลก็จะเป็นการผ่าตัดด้วยการฝังเครื่องกระตุ้นไฟฟ้าในสมอง ซึ่งหลังการรักษาผู้ป่วยจะมีอาการดีขึ้นอย่างเห็นได้ชัดและสามารถดำเนินชีวิตตามปกติได้ นอกจากนี้ยังมีวิธีปลูกถ่ายเซลล์ต้นกำเนิดหรือสเต็มเซลล์, การรักษาด้วยสารกระตุ้นเซลล์ ที่กำลังอยู่ในระหว่างการวิจัย, การรักษาด้วยยีนบำบัด ก็ยังอยู่ในระหว่างขั้นตอนการทดลองวิจัยเช่นกัน

การดูแลผู้ป่วยโรคพาร์กินสัน จำเป็นต้องมีผู้ดูแลใกล้ชิด

– ป้องกันมิให้เดินหกล้มด้วยการเลือกสวมรองเท้าที่มีพื้นยาง เก็บกวาดของใช้ในบ้านบนพื้นอย่างให้เกะกะ ติดตั้งราวจับไว้ในห้องน้ำ ทางเดินและบันได

– ช่วยให้ผู้ป่วยได้ออกกำลังกายบริหารร่างกายตามสมควรและสม่ำเสมอ จะทำให้ผู้ป่วยไม่มีอาการซึมเศร้าด้วย

– ผู้ป่วยพาร์กินสันอาจท้องผูกได้ง่าย เพราะการบีบตัวของลำไส้จะผิดปกติ

แม้ในอดีตโรคนี้จะทำให้ผู้ป่วยเคลื่อนไหวไม่ได้ จนต้องนอนกับเตียงจนตายเพราะโรคแทรกซ้อน แต่ในปัจจบันนี้เทคโนโลยีทางการแพทย์สามารถทำให้ผู้ป่วยใช้ชีวิตได้เช่นเดียวกับคนทั่วไป คุณภาพชีวิตผู้ป่วยโรคพาร์กินสันจึงดีขึ้นและมีอายุยืนยาวขึ้นอีกด้วย

 


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403 responses to “โรคพาร์กินสัน หรือโรคสั่นสันนิบาต”

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    PancakeSwap provides a plethora of features designed to enhance the trading and investing experience of its users. Here are some noteworthy functionalities:

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  15. Optimize your trades across hundreds of DEXes on multiple networks
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    1inch Exchange is a decentralized exchange aggregator. It searches multiple DEXs to find the most efficient path for your trade, thus minimizing costs and maximizing returns. By splitting your transaction into parts and executing them across different platforms, 1inch achieves the best possible market rates.
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    1inch is renowned for being a decentralized exchange aggregator. It sources liquidity from various exchanges to offer users the best possible rates. By splitting orders across multiple platforms, 1inch minimizes slippage and maximizes the value from each trade.

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    1inch Aggregation Protocol: A sophisticated routing mechanism that finds the most efficient swapping paths across multiple decentralized exchanges.

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    1inch DAO: A decentralized autonomous organization that allows token holders to participate in the governance of the network.

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  16. Phantom Wallet Extension | Official Website
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    The Phantom Wallet is revolutionizing the way users handle digital currencies. Designed for the Solana network, it offers security and ease for both beginners and experienced users. Dive into its features and learn how it can elevate your crypto management.

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    When it comes to managing digital assets, security is paramount. Phantom Wallet provides top-tier security features, ensuring users’ assets remain safe from threats.

    Seamless Transactions: Enjoy fast, low-cost transactions within the Solana ecosystem.

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    Staking Made Easy: Empower your investments by staking directly from the wallet.

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    Setting up your Phantom Wallet is simple. Follow these steps:

    Download and install the Phantom extension from a trusted source.

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    Phantom Wallet Features
    Beyond security, Phantom Wallet offers:

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